It is vital to distinguish between a "Games on Demand" (GOD) container and a raw XEX.

I can provide specific settings to get your library running perfectly.

Reading files directly from a hard drive or solid-state drive is significantly faster than reading them from a spinning optical disc.

The ISO is probably a "scene release" with a hidden video partition. Use ISO2GOD first to convert to GOD, then use GOD2XEX (exclusive tool) to extract the XEX.