Always check for orthogonal reactivity . Ensure that the reagent you use in Step 3 doesn't destroy the functional group you carefully installed in Step 1. This is where protecting groups (like TBDMS or Acetals) become essential tools in your mental toolbox.
Not all practice problems are equal. Seek out problems that require multistep reasoning rather than single-answer recall. advanced organic chemistry practice problems
Key concepts
m/z 100, 85, 57, 29
Let's dissect the five most common archetypes found in graduate-level exams (like the ACS Organic Exam, or prelims at top-tier programs). Always check for orthogonal reactivity