Her performance in Nee Pathi Naan Pathi (1991) earned her the Filmfare Award for Best Actress – Tamil .

" (Gentleman, 1993) : A highly popular special appearance in this blockbuster song alongside Prabhu Deva. : Her role in Nee Pathi Naan Pathi

Gouthami debuted in 1987 with the Telugu film Karthika Pournami . Her first Tamil film was Kalyana Kacheri (1987) opposite S. Ve. Shekar, but her major breakthrough in Tamil came with:

Arguably India’s answer to The Godfather , this film is required viewing. Gouthami played the wife of a Mumbai don (Kamal Haasan). Though her screen time is limited, her tragic death scene—where she is shot while embracing her husband—is one of the most haunting moments in Indian cinema. It won her the Tamil Nadu State Film Award for Best Actress.